Endocannabinoids and Prostaglandins Both Contribute to Gonadotropin-releasing 1 Hormone (gnrh) Neuron-gabaergic Afferent Local Feedback Circuits 2 3
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چکیده
Endocannabinoids and prostaglandins both contribute to gonadotropin-releasing 1 hormone (GnRH) neuron-GABAergic afferent local feedback circuits 2 3 Katarzyna M. Glanowska and Suzanne M. Moenter 4 5 Neuroscience Graduate Program, University of Virginia, Department of Molecular and 6 Integrative Physiology, University of Michigan 7 8 Corresponding author: Suzanne M. Moenter, Department of Molecular and Integrative 9 Physiology, University of Michigan, 7725 Med Sci II, 1137 E. Catherine St, Ann Arbor, MI 10 48109-5622 11 734-647-1755 (voice), 734-936-8813 (fax) [email protected] 12 13
منابع مشابه
Endocannabinoids and prostaglandins both contribute to GnRH neuron-GABAergic afferent local feedback circuits.
Gonadotropin-releasing hormone (GnRH) neurons form the final common pathway for central control of fertility. Regulation of GnRH neurons by long-loop gonadal steroid feedback through steroid receptor-expressing afferents such as GABAergic neurons is well studied. Recently, local central feedback circuits regulating GnRH neurons were identified. GnRH neuronal depolarization induces short-term in...
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Introduction: The role of estrogen in the stimulation of gonadotropin-releasing hormone (GnRH) neurons is clear. These neurons do not express estrogen alpha receptors, so other mediator neurons should be present to transmit the positive feedback effect of estrogen to the GnRH neurons. Kisspeptin neurons have an important role in the stimulation of GnRH neurons, so they can be the mediator of...
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تاریخ انتشار 2011